Shaji K Kumar Selected Research

ixazomib

1/2022	Phase 2 trial of ixazomib, cyclophosphamide, and dexamethasone for previously untreated light chain amyloidosis.
1/2021	Oral ixazomib, lenalidomide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma.
1/2021	Final Overall Survival Analysis of the TOURMALINE-MM1 Phase III Trial of Ixazomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma.
7/2020	c-MYC expression and maturity phenotypes are associated with outcome benefit from addition of ixazomib to lenalidomide-dexamethasone in myeloma.
1/2019	Phase 2 study of all-oral ixazomib, cyclophosphamide and low-dose dexamethasone for relapsed/refractory multiple myeloma.
1/2019	Ixazomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma: long-term follow-up including ixazomib maintenance.
12/2018	Ixazomib for the treatment of multiple myeloma.
1/2018	Phase 1/2 trial of ixazomib, cyclophosphamide and dexamethasone in patients with previously untreated symptomatic multiple myeloma.
2/2017	Ixazomib cardiotoxicity: A possible class effect of proteasome inhibitors.
11/2016	Randomized phase 2 trial of ixazomib and dexamethasone in relapsed multiple myeloma not refractory to bortezomib.

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Shaji K Kumar Research Topics

Disease

108	Multiple Myeloma 10/2022 - 07/2004
55	Immunoglobulin Light-chain Amyloidosis 01/2022 - 04/2006
24	Amyloidosis 11/2022 - 05/2007
21	Neoplasms (Cancer) 01/2022 - 11/2007
7	Disease Progression 04/2022 - 07/2004
5	Proteinuria 01/2022 - 05/2007
5	Residual Neoplasm 10/2021 - 11/2016
5	Thrombocytopenia (Thrombopenia) 12/2020 - 01/2007
4	Monoclonal Gammopathy of Undetermined Significance 01/2022 - 05/2010
4	POEMS Syndrome (Syndrome, POEMS) 01/2022 - 05/2008
4	Neutropenia 11/2021 - 01/2007
4	Smoldering Multiple Myeloma 01/2020 - 01/2008
3	Infections 02/2022 - 10/2018
3	Trisomy (Trisomies) 12/2020 - 01/2019
3	Waldenstrom Macroglobulinemia (Macroglobulinemia) 01/2018 - 09/2010
3	Peripheral Nervous System Diseases (PNS Diseases) 01/2017 - 05/2008
3	Paraproteinemias (Monoclonal Gammopathy) 05/2016 - 01/2012
2	Vitamin D Deficiency 01/2022 - 07/2009
2	Thrombocytosis (Thrombocythemia) 01/2022 - 05/2008
2	Chromosome Aberrations (Chromosome Abnormalities) 12/2021 - 12/2018
2	Carcinogenesis 12/2021 - 10/2009
2	Pneumonia (Pneumonitis) 11/2021 - 12/2020
2	B-Cell Lymphoma (Lymphoma, B Cell) 10/2021 - 01/2021
2	Plasma Cell Leukemia 01/2021 - 02/2018
2	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 01/2021 - 01/2020
2	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 08/2019
2	Albuminuria 12/2020 - 11/2016
2	Anemia 11/2020 - 12/2019
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 11/2020 - 01/2018
2	Fever (Fevers) 01/2019 - 10/2018
2	Acute Kidney Injury (Acute Renal Failure) 06/2018 - 01/2016
2	Lymphoma (Lymphomas) 01/2018 - 09/2017
2	Cardiotoxicity 02/2017 - 10/2010
2	Plasmacytoma 01/2017 - 04/2008
2	Fatigue 08/2014 - 01/2007
2	Vomiting 08/2014 - 10/2013
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2022
1	Castleman Disease (Castleman's Disease) 01/2022
1	Hypoalbuminemia 01/2022
1	Thrombosis (Thrombus) 01/2022
1	Thromboembolism 01/2022

Drug/Important Bio-Agent (IBA)

28	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 01/2007
21	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2006
19	Lenalidomide (CC 5013)FDA Link 01/2022 - 01/2007
15	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 01/2021 - 05/2007
12	ixazomibIBA 01/2022 - 08/2014
12	Bortezomib (Velcade)FDA Link 01/2022 - 02/2012
11	Pharmaceutical PreparationsIBA 01/2022 - 10/2010
9	Immunoglobulins (Immunoglobulin)IBA 02/2022 - 04/2006
9	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2010
9	Proteasome InhibitorsIBA 01/2022 - 08/2014
8	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 08/2011
8	Melphalan (Alkeran)FDA LinkGeneric 01/2019 - 06/2010
7	Immunoglobulin M (IgM)IBA 01/2021 - 09/2010
7	Amyloid (Amyloid Fibrils)IBA 01/2020 - 04/2006
6	Immunomodulating AgentsIBA 01/2022 - 03/2012
6	daratumumabIBA 11/2021 - 11/2017
6	venetoclaxIBA 10/2021 - 02/2018
5	Troponin T (Troponin T1)IBA 01/2021 - 05/2007
5	pro-brain natriuretic peptide (1-76)IBA 01/2021 - 10/2010
3	carfilzomibIBA 10/2021 - 01/2020
3	pomalidomideIBA 03/2021 - 06/2012
3	AlbuminsIBA 12/2020 - 05/2007
3	CreatinineIBA 12/2020 - 07/2009
3	Monoclonal AntibodiesIBA 01/2019 - 09/2006
3	Sorafenib (BAY 43-9006)FDA Link 10/2013 - 10/2007
2	25-hydroxyvitamin DIBA 01/2022 - 07/2009
2	Chimeric Antigen ReceptorsIBA 01/2022 - 01/2021
2	Vitamin D FDA LinkGeneric 01/2022 - 07/2009
2	Hemoglobins (Hemoglobin)IBA 01/2022 - 01/2020
2	Drug CombinationsIBA 01/2022 - 10/2019
2	EnzymesIBA 01/2022 - 01/2022
2	hydroxide ionIBA 01/2022 - 07/2009
2	Glutamine (L-Glutamine)FDA Link 12/2020 - 11/2018
2	Phosphotransferases (Kinase)IBA 12/2019 - 10/2007
2	Histone Deacetylase InhibitorsIBA 10/2019 - 01/2016
2	TroponinIBA 10/2019 - 06/2015
2	Propylene Glycol (1,2 Propanediol)FDA LinkGeneric 01/2019 - 01/2019
2	Biological ProductsIBA 01/2019 - 01/2016
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019 - 06/2015
2	thiamine triphosphorate (TTP)IBA 11/2018 - 04/2008
2	Congo RedIBA 11/2017 - 10/2016
2	AntigensIBA 01/2017 - 11/2016
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2013 - 05/2008
2	Alkylating AgentsIBA 05/2012 - 03/2012
2	Rituximab (Mabthera)FDA Link 09/2010 - 09/2006
1	1,25-dihydroxyvitamin DIBA 01/2022
1	Immunoconjugates (Immunoconjugate)IBA 01/2022
1	Bispecific AntibodiesIBA 01/2022
1	VitaminsIBA 01/2022
1	Vitamin D-Binding ProteinIBA 01/2022
1	Thalidomide (Thalomid)FDA Link 01/2022

Therapy/Procedure

86	Therapeutics 11/2022 - 07/2004
44	Stem Cell Transplantation 11/2022 - 05/2007
11	Drug Therapy (Chemotherapy) 01/2022 - 03/2006
4	Transplantation 10/2022 - 10/2007
4	Hematopoietic Stem Cell Transplantation 07/2020 - 03/2006
3	Precision Medicine 01/2022 - 11/2020
2	Autologous Transplantation 01/2017 - 03/2012
2	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) 02/2012 - 04/2006